Product Details
pqsfinder: an R/Bioconductor package for identification of potential quadruplex forming sequences
Created: 2016
Czech title
pqsfinder: R/Bioconductor balíček pro identifikaci sekvencí tvořících kvadruplexy
Type
software
License
optional - free
Authors
Hon Jiří, Ing., Ph.D. (DIFS FIT BUT)
Lexa Matej, Ing., Ph.D. (FI MUNI)
Martínek Tomáš, doc. Ing., Ph.D. (DCSY FIT BUT)
Zendulka Jaroslav, doc. Ing., CSc. (DIFS FIT BUT)
Lexa Matej, Ing., Ph.D. (FI MUNI)
Martínek Tomáš, doc. Ing., Ph.D. (DCSY FIT BUT)
Zendulka Jaroslav, doc. Ing., CSc. (DIFS FIT BUT)
Keywords
G-quadruplex; quadruplex; DNA; R; Bioconductor; pattern matching; searching; annotation
Description
The main functionality of the this package is to detect DNA sequence patterns that are likely to fold into an intramolecular G-quadruplex (G4). Unlike many other approaches, this package is able to detect sequences responsible for G4s folded from imperfect G-runs containing bulges or mismatches and as such is more sensitive than competing algorithms.
Location
Licence
Free software under the terms of BSD license (see http://www.opensource.org/licenses/bsd-license.php).
Projects
Research and application of advanced methods in ICT (FIT-S-14-2299)
Departments