Publication Details

Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments

RUDOLFOVÁ Ivana, ZENDULKA Jaroslav and LEXA Matej. Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments. In: Information Technology in Bio- and Medical Informatics, ITBAM 2010. Lecture Notes in Computer Science, vol. 6266. Heidelberg: Springer Verlag, 2010, pp. 94-101. ISBN 978-3-642-15019-7.
Czech title
Shlukování proteinových substruktur pro nalezení nových sekvenčně-strukturních fragmentů
Type
conference paper
Language
english
Authors
Rudolfová Ivana, Ing., Ph.D. (DIFS FIT BUT)
Zendulka Jaroslav, doc. Ing., CSc. (DIFS FIT BUT)
Lexa Matej, Ing., Ph.D. (DCSY FIT BUT)
Keywords

Clustering, density-based clustering, clustering of protein substructures, sequence-structure relationships in proteins

Abstract

In this paper, we propose a novel method for clustering of protein substructures that we developed to study the relationships between protein sequences and their corresponding structures. We show the results of the comparison to other commonly used methods for clustering of protein structures. Finally, we outline a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.

Published
2010
Pages
94-101
Proceedings
Information Technology in Bio- and Medical Informatics, ITBAM 2010
Series
Lecture Notes in Computer Science
Volume
6266
Conference
International Conference on Information Technology in Bio- and Medical Informatics, Bilbao, ES
ISBN
978-3-642-15019-7
Publisher
Springer Verlag
Place
Heidelberg, DE
DOI
10.1007/978-3-642-15020-3_9
EID Scopus
2-s2.0-78049470351
BibTeX 
@INPROCEEDINGS{FITPUB9338,
   author = "Ivana Rudolfov\'{a} and Jaroslav Zendulka and Matej Lexa",
   title = "Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments",
   pages = "94--101",
   booktitle = "Information Technology in Bio- and Medical Informatics, ITBAM 2010",
   series = "Lecture Notes in Computer Science",
   volume = 6266,
   year = 2010,
   location = "Heidelberg, DE",
   publisher = "Springer Verlag",
   ISBN = "978-3-642-15019-7",
   doi = "10.1007/978-3-642-15020-3\_9",
   language = "english",
   url = "https://www.fit.vut.cz/research/publication/9338"
}
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