Course details
Molecular Genetics I
BC_MOG1 FCH BC_MOG1 Acad. year 2019/2020 Winter semester 4 credits
History of molecular genetics. Genetic information and the genetic code. Molecular structure of procaryotic and eucaryotic genome. Replication and transcription of procaryotic and eucaryotic genome. Postranscriptional modification and processing of RNA. Translation and posttranslational processing. Regulation of gene expression. Molecular basis of cancerogenesis (oncogenes, antioncogenes). Molecular mechanisms of mutagenesis and recombination. Mobile elements. Repair mechanisms of damaged DNA. Basic methods of molecular genetics. DNA cloning. Gene engineering and transgenic organisms.
Guarantor
Language of instruction
Completion
Time span
- 26 hrs lectures
Department
Lecturer
Subject specific learning outcomes and competences
The basic knowledge of molecular biology, using methods of molecular biology and gene engineering in the research area, in industry, agriculture and medicine.
Learning objectives
This lecture is conceived as an introduction into molecular biology and genetics and gives the explanation of processes on molecular level in relation to the basic functions of living systems. The second part of the lecture is focused on basic methods of molecular genetics and their applications in gene engineering which is a main tool of modern biotechnologies.
Prerequisite knowledge and skills
The structure and basic functions of living systems, their reproduction, cell chemistry, structure and function of biomacromolecules.
Progress assessment
Oral exam
Teaching methods and criteria
The course uses teaching methods in form of Lecture - 2 teaching hours per week. The e-learning system (LMS Moodle) is available to teachers and students.
Controlled instruction
Lectures are optional, no control tests during the semester.
Course inclusion in study plans